Advanced Medical
Science

Diagnostic & Preventative

At The Roxbury Institute, our Center for Diagnostic and Preventative Medicine was built for patients who have spent years searching for answers. Led by internationally recognized endocrinologist Dr. Karen L. Herbst, our Tucson center is where complex, chronically misunderstood conditions finally meet the depth of expertise they deserve. Your journey toward clarity, accurate diagnosis, and lasting health starts here.

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Our Approach

to Diagnostic & Preventative Care

We believe that the right diagnosis changes everything. For patients living with lipedema, Dercum's disease, or other diseases of adipose and connective tissue, the path forward begins with being truly seen and genuinely heard. Our approach goes far beyond symptom management.

We investigate the metabolic, hormonal, immunological, and genetic factors that shape each patient's experience, then build a care strategy around that full picture. No two patients are alike, and no two treatment plans should be either.

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Conditions & Services

Our center brings together advanced diagnostics, research-informed protocols, and individualized preventative care for a range of complex fat and connective tissue disorders.

Conditions We Treat

Lipedema

Dercum's Disease

Familial Multiple Lipomatosis

Multiple Symmetric Lipomatosis

Ehlers-Danlos Syndrome

Mast Cell Activation Syndrome

Lipolymphedema

Other diseases of adipose connective tissue

Diagnostic Services

Expert clinical evaluation and staging

Metabolic and hormonal assessment

Immune system and inflammatory marker analysis

Genetic evaluation for connective tissue disorders

ICD-10-coded diagnosis for lipedema and Dercum's disease

Preventative & Therapeutic Services

CVAC Hypobaric Treatment

Mediator Release Testing (MRT) for food sensitivities and inflammation

Individualized nutrition and inflammation management protocols

Disease progression monitoring and prevention planning

Research & Clinical Programs

Active clinical trials and research studies

Access to novel therapies and clinical breakthroughs

Collaboration with Dr. David Amron and the ALT surgical team

Participation in national and international lipedema research

Why Choose TRI
for Diagnostic & Preventative Care

Our commitment to excellence sets us apart in every aspect of surgical care.

01
A Specialist You Can Trust
Dr. Karen L. Herbst is one of the few physicians in the world who has spent over two decades focused exclusively on lipedema, Dercum's disease, and related conditions. Her depth of knowledge is unmatched in the field.
02
Research That Reaches You Directly
As Head of Research at The Roxbury Institute, Dr. Herbst brings the latest findings from her research directly into clinical practice. Her patients benefit from insights that are often years ahead of mainstream medicine.
03
Care Built Around You
Every patient presents differently. We take the time to understand your full medical history, your symptoms, and your goals before building a plan that is yours alone. We are your partners from your first appointment forward.
04
A Diagnosis That Opens Doors
For many of our patients, receiving an accurate diagnosis is life-changing, helping patients access appropriate care, insurance coverage, and peace of mind.

Meet Our Diagnostic & Preventative Team

Karen L. Herbst, MD, PhD

Head of Research & Director of Diagnostic and Preventative Medicine

Dr. Karen L. Herbst, a prominent board-certified endocrinologist, serves as the Head of Research and Director of Diagnostic and Preventative Medicine at The Roxbury Institute in Tucson, Arizona, home to the Advanced Lipedema Treatment (ALT) program.

Areas of Expertise
Research & Innovation
Clinical Research
Clinical Trials
Diagnostic Medicine
Metabolic Medicine
Dercum's Disease
Fat Disorders
Advanced Diagnostics
CVAC Treatments
Lipedema
Lipedema Diagnosis
Lipedema Conservative Treatment Plans

Karen L. Herbst, MD, PhD

Head of Research & Director of Diagnostic and Preventative Medicine

Dr. Karen L. Herbst, a prominent board-certified endocrinologist, serves as the Head of Research and Director of Diagnostic and Preventative Medicine at The Roxbury Institute in Tucson, Arizona, home to the Advanced Lipedema Treatment (ALT) program.

Areas of Expertise
Research & Innovation
Clinical Research
Clinical Trials
Diagnostic Medicine
Metabolic Medicine
Dercum's Disease
Fat Disorders
Advanced Diagnostics
CVAC Treatments
Lipedema
Lipedema Diagnosis
Lipedema Conservative Treatment Plans

Michele
Blecher, MS NP

MSN, NP-C

Michele Blecher is a highly skilled Nurse Practitioner specializing in specializing in Lipedema diagnosis, Lipedema conesvative treatment plans, and pre and post surgical care at The Roxbury Institute in Los Angeles, CA. With over two decades of clinical experience across multiple specialties, she brings a comprehensive understanding of patient care, surgical protocols, and medical management to her practice.

Areas of Expertise
Post-Surgical Care
Lipedema Diagnosis
Lipedema Conservative Treatment Plans
Non-Surgical Treatment Plans

Michele
Blecher, MS NP

MSN, NP-C

Michele Blecher is a highly skilled Nurse Practitioner specializing in specializing in Lipedema diagnosis, Lipedema conesvative treatment plans, and pre and post surgical care at The Roxbury Institute in Los Angeles, CA. With over two decades of clinical experience across multiple specialties, she brings a comprehensive understanding of patient care, surgical protocols, and medical management to her practice.

Areas of Expertise
Post-Surgical Care
Lipedema Diagnosis
Lipedema Conservative Treatment Plans
Non-Surgical Treatment Plans

Dr. David Amron, MD

Founder & Medical Director

Board-certified dermatologic surgeon and the pioneer of lipedema surgery in the United States. Dr. Amron's innovative techniques and dedication to advancing medical knowledge have established him as a global leader in his field. As founder of The Roxbury Institute and star of Netflix's "Celebrity Plastic Surgeons of Beverly Hills," he has dedicated his career to setting new standards in patient care and surgical excellence.

Areas of Expertise
Lipedema Surgery
Body Contouring
Advanced Liposuction
Research & Innovation

Dr. Jennifer Ahdout, MD

Director of Medical & Cosmetic Dermatology

Board-certified dermatologic surgeon and the pioneer of lipedema surgery in the United States. Dr. Amron's innovative techniques and dedication to advancing medical knowledge have established him as a global leader in his field. As founder of The Roxbury Institute and star of Netflix's "Celebrity Plastic Surgeons of Beverly Hills," he has dedicated his career to setting new standards in patient care and surgical excellence.

Areas of Expertise
Lipedema Surgery
Body Contouring
Advanced Liposuction
Research & Innovation

Dr. Shawn Moshrefi, MD

Director of Plastic Surgery

Stanford-trained, board-certified plastic and reconstructive surgeon bringing exceptional expertise to complex aesthetic and reconstructive procedures. Dr. Moshrefi's distinguished background and commitment to surgical excellence make him a trusted choice for patients seeking the highest quality outcomes. His particular expertise in facial rejuvenation and body contouring has earned recognition from peers and patients worldwide.

Areas of Expertise
Facial Rejuvenation
Breast Surgery
Body Contouring
Reconstructive Surgery

Looking to Schedule a Consultation?

If you have been living with unexplained symptoms, a difficult-to-diagnose condition, or a fat disorder that has not received the attention it deserves, we are ready to help. Schedule a consultation with Dr. Herbst and our team in Tucson to take your first step toward real answers.

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